EDUCATION:

Institute of Organic Chemistry, NAS of Ukraine, Kyiv

Ph.D. Organoelement chemistry

Thesis title: Phosphorylated 1,2,4-triazoles

Defense Date: June, 2015

National Technical University of Ukraine “Kyiv Polytechnic Institute”, Kyiv, Ukraine

Master of Science, Organic Chemistry and Chemical Technology of Organic Substances

Graduation Date: June, 2010 GPA: 5.0. Finished with Cum Laude diploma

RESEARCH EXPERIENCE:

Course Project (January 2006 – August 2006)

Organic Chemistry Lab, National Technical University of Ukraine “Kyiv Polytechnic Institute”

• Synthesis and investigation of adamantane derivatives.

Laboratory Assistant (September 2006 – October 2010)

Institute of Organic Chemistry, NAS of Ukraine

• Synthesis and investigation of phosphorus-containing compounds: phosphanylated heterocycles, phosphinines, etc.

PhD Student (November 2010 – October 2013)

Institute of Organic Chemistry, NAS of Ukraine

• Synthesis of N-phosphanylated triazol-5-ylidenes and C-phosphanylated heterocycles.

Researcher (June – August 2014)

Department of Chemistry, University of Helsinki, Finland

• Synthesis of neonicotinoid analogs based on fluorinated cyclic amines and cycloalkylamines.

Researcher (April – May 2015)

Department of Chemistry, University of Helsinki, Finland

• Computational studies of fluorinated neonicotinoid analogs.

Researcher (June – August 2015)

Institute of Polymers, Composites and Biomaterials, Italian National Research Council

• Quantum chemical calculations for prediction of properties and stability of 2D black phosphorus nanoparticle-containing polymeric nanocomposites.

Researcher (November – December 2015)

Department of Chemistry, University of Helsinki, Finland

• Molecular docking and quantum chemical studies based on the results of biological tests of previously synthesized neonicotinoid analogs.

Researcher (January – March 2018)

Department of Chemistry, Ibn Tofail University, Morocco

• Molecular docking studies for the design of novel antileishmanial drugs

• Quantum-chemical investigations of Nb and Sb clusters

Researcher (August – May 2018)

Physics and Astronomy Department, Michigan State University, USA

• Quantum-chemical calculations of 2D materials.

Researcher (November 2013 – present)

Institute of Organic Chemistry, NAS of Ukraine

• Quantum-chemical investigation of mechanisms of formation and reactions of N- and C-phosphanylated heterocycles and N-heterocyclic carbenes, diaminocarbenes, and other organic compounds.

• Carrying out quantum-chemical calculations on various small organic molecules using Gaussian, Turbomole, ORCA and Crystal09 packages.

• Molecular dynamics simulations for conformational sampling of small organic molecules and research of proteins using Gromacs and Amber packages.

PUBLICATIONS:

• Zarudnitskii, E.V.; Kyrylchuk, A.A.; Huryeva, A.N. et al. Synthesis of 4,5-dihydroimidazo[5,1-c][1,4,2]benzodiazaphosphinines. Heteroat. Chem. 2011, 22, 91–95.

• Marchenko, A.P.; Koidan, H.N.; Zarudnitskii, E.V.; Hurieva, A.N.; Kirilchuk, A.A. et al. Stable N-Phosphorylated 1,2,4-Triazol-5-ylidenes: Novel Ligands for Metal Complexes. Organometallics 2012, 31, 8257–8264.

• Kirilchuk, A.A.; Marchenko, A.P.; Koidan, H.G. et al.
  Stable N-Phosphorylated Triazol-5-Ylidenes. Phosphorus. Sulfur. Silicon Relat. Elem. 2013, 188, 254–255.

• Kirilchuk, A.A.; Yurchenko, A.A.; Vlasenko, Y.G. et al. Synthesis and Structure of Phosphanylated Bis-Triazoles as Potential Ligands for Chiral Catalysts. Chem. Heterocycl. Compd. 2015, 1559-1566.

• Kirilchuk, A.A.; Yurchenko, A.A.; Kostyuk, A.N. et al.
  1,2-migration in N-phosphano functionalized N-heterocyclic carbenes. J. Comput. Chem. 2015, 36, 42–48.

• Marchenko, A.P.; Koidan, H.N.; Kirilchuk, A.A. et al. Investigation of N- and C-Phosphanylation of [1,2,4]Triazolo[4,3- a ]pyridines. Heteroat. Chem. 2015, 4, 277-289.

• Shevchenko, I.V.; Turcheniuk, K.V.; Kirilchuk, A.A. et al.
  On the Reaction of Diaminocarbenes with Aroylimines. J. Org. Chem. 2015, 80, 1387–1394.

• Kirilchuk, A.A., Rozhenko, A.B., Leszczynski, J On Structure and Stability of Pyrimidine Ylidenes and Their Homologues. Comp. Theor. Chem. 2017, 1103, 83–91.

AWARDS:

2015     L. M. Markovsky Award for Outstanding Research Work, Department of Chemistry, NAS of Ukraine

2016     NAS of Ukraine Award for Young Scientists

2018      Fulbright Foreign Student Program Fellowship

MENTORING:

2015 – 2016     Managed and mentored master student, who defended her thesis cum laude. Thesis title: “Quantum-chemical calculation of pK_a values for the series of fluoro-substituted amines and bisphosphonic acids”

2017 – 2018     Managed and mentored master student, who defended his thesis cum laude. Thesis title: “Quantum-chemical investigations of mechanisms of trimethylsilylchloride-mediated heterocyclization reactions”